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FlyChip
Functional Genomics for Drosophila
Cambridge Systems Biology Centre, Tennis Court Road, Cambridge, CB2 1QR, UK  [map]
Tel: +44 (0)1223-760280.   Fax: +44 (0)1223-760241.

Reviews & research articles

2008

Russell, S. (2008). SNPing and chipping away at the fly genome. Nat Methods. 5(4):295-6. (PubMed)

2007

Sykacek, P., Clarkson, R., Print, C., Furlong, R., Micklem, G. (2007). Bayesian modelling of shared gene function. Bioinformatics 23(15):1936-44.(PubMed)

Baker, D.A., Meadows, L.A., Wang, J., Dow, J.A.T., Russell, S. (2007). Variable sexually dimorphic gene-expression in laboratory strains of Drosophila melanogaster. BMC Genomics 8:454 (PubMed)

Adryan, B., Woerfel, G., Birch-Machin, I., Gao, S., Quick, M., Meadows, L., Russell, S., White, R. (2007). Genomic mapping of Suppressor of Hair-wing binding sites in Drosophila. Genome Biol. 8(8):R167. (PubMed)

Holohan, E.E., Kwong, C., Bartkuhn, M., Herold, M., Renkawitz, R., Russell, S., White. R. (2007). CTCF genomic binding sites in Drosophila and the organisation of the Bithorax Complex. PLoS Genet. 3(7):e112. (PubMed)

Samsonova, A.A., Niranjan, M., Russell, S., Brazma. A. (2007). Prediction of gene expression in embryonic structures of Drosophila melanogaster. PLoS Comput Biol. 3(7):e144. (PubMed)

Lyne, R., Smith, R., Rutherford, K., Wakeling, M., Varley, A., Gullier, F., Janssens, H., Wenyan, J., McLaren, P., North, P., Rana, D., Riley, T., Sullivan, J., Watkins, X., Woodbridge, M., Lilley, K., Russell, S., Ashburner, M., Mizguchi, K., Micklem, G. (2007). FlyMine: an integrated database for Drosophila and Anopheles genomics. Genome Biol. 8(7):R129 (PubMed) (FlyMine)

2006

Le Brigand, K., Russell, R., Moreilhon, C., Rouillard, J.M., Jost, B., Amiot, F., Magnone, V., Bole-Feysot, C., Rostagno, P., Virolle, V., Defamie, V., Dessen, P., Williams, G., Lyons, P., Rios, G., Mari, B., Gulari, E., Kastner, P., Gidrol, X., Freeman, T.C., Barbry, P. (2006). An open-access long oligonucleotide microarray resource for analysis of the human and mouse transcriptomes. Nucleic Acids Res. 34(12):e87. (PubMed)

Russell, S. (2006). Learning to fly - getting the best out of microarrays. Mol. Biosyst. 2(9):402-5. (PubMed)

Choksi, S.P., Southall, T.D., Bossing, T., Edoff, K., de Wit, E., Fischer, B.E., van Steensel, B., Micklem, G., Brand, A.H. (2006). Prospero acts as a binary switch between self-renewal and differentiation in Drosophila neural stem cells. Dev Cell. 11(6):775-89. (PubMed)

Kreil, D.P., Russell, R.R., Russell, S. (2006). Microarray oligonucleotide-probes. Methods Enzymol. 410:73-98. (PubMed) (Supplement)

Auburn, R.P., Russell, R., Fischer, B., Meadows, L.A., Sevillano Matilla, S., Russell, S. (2006). SimArray: a user-friendly and user-configurable microarray design tool. BMC Bioinformatics. 7:102. (PubMed) (SimArray)

Ryder, E., Jackson, R., Ferguson-Smith, A., Russell, S. (2006). MAMMOT - a set of tools for the design, management and visualisation of genomic tiling arrays. Bioinformatics. 22(7):883-884. (PubMed) (MAMMOT)

2005

Page, A.R., Kovacs, A., Deak, P., Torok, T., Kiss, I., Dario, P., Bastos, C., Batista, P., Gomes, R., Ohkura, H., Russell, S.,Glover D.M. (2005). Spotted-dick, a zinc-finger protein of Drosophila required for expression of Orc4 and S phase. EMBO J. 24(24):4304-4315. (PubMed)

External RNA Controls Consortium (2005). Proposed methods for testing and selecting the ERCC external RNA controls. BMC Genomics 6:150. (PubMed)

McKimmie, C., Woerfel, G., Russell S. (2005). Conserved genomic organization of group B Sox genes in insects. BMC Genetics. 6(1):26. (PubMed)

Sykacek, P., Furlong, R.A., Micklem, G. (2005). A friendly statistics package for microarray analysis. Bioinformatics. 21(21):4069-4070. (PubMed) (FSPMA)

Doney A.S., Fischer B., Lee S., Morris A.D., Leese G.P., Palmer C.N. (2005). Association of common variation in the PPARA gene with incident myocardial infarction in individuals with type 2 diabetes: A Go-DARTS study. Nucl Recept. 3(1):4 (PubMed)

Cecil J.E., Fischer B., Doney A.S., Hetherington M., Watt P., Wrieden W., Bolton-Smith C., Palmer C.N. (2005). The Pro12Ala and C-681G variants of the PPARG locus are associated with opposing growth phenotypes in young schoolchildren. Diabetologia. 48(8):1496-1502. (PubMed)

Birch-Machin, I., Gao, S., Huen, D., McGirr, R., White, R.A.H., Russell, S. (2005). Genomic analysis of heat-shock factor targets in Drosophila. Genome Biology 6:R63. (PubMed)

Auburn, R.P., Kreil, D. P., Meadows, L. A., Fischer, B., Sevillano Matilla, S., Russell, S. (2005). Robotic spotting of cDNA and oligonucleotide microarrays. Trends Biotechnol. 23(7):374-379. (PubMed)

Woolfson, A., Stebbing, J., Tom, B., Stoner, K., Gilks, W., Kreil, D.P., Mulligan, S., Belov, L., Chrisp, J., Errington, W., Wildfire, A., Erber, W., Bower, M., Gazzard, B., Christopherson, R., Scott, M. (2005). Conservation of unique cell surface CD antigen mosaics in HIV-1 infected individuals. Blood. 106(3):1003-1007.(PubMed)

Kreil, D.P., Russell, R.R.(2005). There is no silver bullet--a guide to low-level data transforms and normalisation methods for microarray data. Brief Bioinform.6(1):86-97. (PubMed)

2004

Kanno, T., Mette, M.F., Kreil, D.P., Aufsatz, W., Matzke, M., Matzke, A.J. (2004). Involvement of putative SNF2 chromatin remodeling protein DRD1 in RNA-directed DNA methylation. Curr Biol. 14(9):801-805. (PubMed)

Doney, A.S., Fischer, B., Leese, G., Morris, A.D., Palmer, C.N. (2004). Cardiovascular risk in type 2 diabetes is associated with variation at the PPARG locus: a Go-DARTS study. Arterioscler Thromb Vasc Biol. 24(12):2403-2407. (PubMed)

Saidi, S.A., Holland, C.M., Kreil, D.P., MacKay, D.J., Charnock-Jones, D.S., Print, C.G., Smith, S.K. (2004). Independent component analysis of microarray data in the study of endometrial cancer. Oncogene. 23(39):6677-6683. (PubMed)

Ryder, E., Blows, F., Ashburner, M., Bautista-Llacer, R., Coulson, D., Drummond, J., Webster, J., Gubb, D., Gunton, N., Johnson, G., O'Kane, C.J., Huen, D., Sharma, P., Asztalos, Z., Baisch, H., Schulze, J., Kube, M., Kittlaus, K., Reuter, G., Maroy, P., Szidonya, J., Rasmuson-Lestander, A., Ekstrom, K., Dickson, B., Hugentobler, C., Stocker, H., Hafen, E., Lepesant, J.A., Pflugfelder, G., Heisenberg, M., Mechler, B., Serras, F., Corominas, M., Schneuwly, S., Preat, T., Roote, J., Russell, S. (2004). The DrosDel collection: a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster. Genetics. 167(2):797-813. (PubMed)

Doney, A.S., Fischer, B., Cecil, J.E., Boylan, K., McGuigan, F.E., Ralston, S.H., Morris, A.D., Palmer, C.N. (2004). Association of the Pro12Ala and C1431T variants of PPARG and their haplotypes with susceptibility to Type 2 diabetes. Diabetologia. 47(3):555-558. (PubMed)

Karp, N.A., Kreil, D.P., Lilley, K.S. (2004). Determining a significant change in protein expression with DeCyder during a pair-wise comparison using two-dimensional difference gel electrophoresis. Proteomics. 4(5):1421-1432. (PubMed)

Ying, L., White, S.S., Bruckbauer, A., Meadows, L., Korchev, Y.E., Klenerman, D. (2004). Frequency and voltage dependence of the dielectrophoretic trapping of short lengths of DNA and dCTP in a nanopipette. Biophys. J. 86(2): 1018-1027. (PubMed)

Doney, A.S., Fischer, B., Cecil, J.E., Cohen, P.T., Boyle, D.I., Leese, G., Morris, A.D., Palmer, C.N. (2004). Male preponderance in early diagnosed type 2 diabetes is associated with the ARE insertion/deletion polymorphism in the PPP1R3A locus. BMC Genet. 4(1):11.(PubMed)

Kreil, D.P., Karp, N.A., Lilley, K.S.. (2004). DNA microarray normalization methods can remove bias from differential protein expression analysis of 2D difference gel electrophoresis results. Bioinformatics. 20(13):2026-2034. (PubMed)

2003

Russell, R. (2003). Designing microarray oligonucleotide probes. Brief Bioinform. 4(4):361-367. (PubMed)

Ryder, E., Russell, S. (2003). Transposable elements as tools for genomics and genetics in Drosophila. Brief Funct Genomic Proteomic. 2(1):57-71. (PubMed)

Kreil, D.P., Ouzounis, C.A. (2003).Comparison of sequence masking algorithms and the detection of biased protein sequence regions. Bioinformatics. 19(13):1672-1681. (PubMed)

2002

Overton, P.M., Meadows, L.A., Urban, J., Russell, S. (2002). Evidence for differential and redundant function of the Sox genes Dichaete and SoxN during CNS development in Drosophila. Development 129(18):4219-4228. (PubMed)

Doney A., Fischer B., Frew D., Cumming A., Flavell D.M., World M., Montgomery H.E., Boyle D., Morris A., Palmer C.N. (2002). Haplotype analysis of the PPARgamma Pro12Ala and C1431T variants reveals opposing associations with body weight. BMC Genet. 13:3:21. (PubMed)